POLIOMYELITIS IN CHIMPANZEES
نویسندگان
چکیده
منابع مشابه
Poliomyelitis in Chimpanzees
The response of eighteen chimpanzees to poliomyelitis virus administered orally and cutaneously has been studied. There were no signs of weakness or paralysis in any of the animals. Sixteen of the eighteen (89 per cent) became infected as measured by intestinal carriage of virus. Only one of twelve was reinfected when challenged with an homologous (or homotypic) strain by the same routes, but s...
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This report is concerned with the production of subclinical poliomyelitis in the chimpanzee, and immunity to such infection. Subclinical infection was produced in eight chimpanzees by the administration of virus orally or intracutaneously, and was measured by the production of a virus carrier state and the development of neutralizing antibodies. Immunity was tested by attempting to induce the c...
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Poliomyelitis (polio) is a highly infectious viral disease, which mainly affects young children. The virus is transmitted by person-to-person spread mainly through the faecal-oral route or, less frequently, by a common vehicle (e.g. contaminated water or food) and multiplies in the intestine, from where it can invade the nervous system and can cause paralysis. Initial symptoms of polio include ...
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The Epidemiology of poliomgelitis has been investigated in our country Pasteur Institute; the incidence of Poliomgelitis, after the age of 4 years i's rare, in Iran. Passive antibody of maternal origin do not interfere with production of active antibody after immunization. Inactivated Polio Vaccine (salk) has been effective in reducing the incidence of poliomgelitis by approximately 90 per ...
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1. The murine virus may be grown in embryonic mouse brain-serum ultrafiltrate cultures. The virus fails to grow in embryonic chick tissue cultures or in fertilized egg preparations. 2. Some relationship can be demonstrated between the amount of nervous tissue and the infectivity of the culture. 3. Optimum titers of virus potency (10(-6)) can be obtained by adjusting the pH of the growing cultur...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1950
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.91.6.573